Grekos kills again

Image source: Mugshots dot com

A friend of the blog just forwarded me a link to a CNN report on the latest grim development in the Zannos Grekos case, in which the Florida state medical board has now imposed an emergency suspension of his license after yet another patient died in his care. The Naples News further reports that the county sheriff is launching a criminal investigation into his (mal)practice. This time, an elderly patient is reported to have died during an illegal, expensive and unscientific procedure for pulmonary hypertension that Grekos advertises as involving processed stem cells he has named "regenocytes."  The emergency action by the medical board follows their emergency restriction of his license last March, after a different elderly patient died within days after receiving a lethal injection of a purported stem cell concentrate at his hands. Before getting the stem cell itch, Grekos had previously killed another patient back in 1997*, through simple neglect. 

Don Margolis, griefer extraordinaire and Grekos' business mentor, is going to have to start shopping for a new member for his advisory board. 

"Regenocyte Adult Stem Cell Therapy is safe, highly effective and presents minimal risk!" 

The identity of the deceased patient is being kept confidential for now, but the Lee County sheriff stated that he had traveled to Bonita Springs, where Grekos' practice was located. I have no doubt that he was very sick already, and it is too soon to determine whether the cause of death was an embolism caused by whatever Grekos injected, or some other complication relating to the anesthesia, surgical stress, or plain old incompetence. 

But what is clear is that doctors who beguile the trusting with simplistic pseudoscience, who jeopardize and impoverish their patients in pursuit of easy cash, and who excuse their refusal to proceed cautiously and scientifically as a right protected in the practice of medicine, are no different from the quacksalvers of yore. These are not bold pioneers - we need to recognize them for the base and craven swindlers they are.  


*Note: a previous version of the post indicated that this death had taken place in 2001.
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UPDATE (March 19, 2012): The Naples News has reported that Zannos Grekos' latest attorney is asserting that the most recent patient death connected to Regenocyte was not from a stem cell injection, as the patient had only received a liopsuction (presumably to harvest what Grekos advertises as stem cells), and that the procedure was performed by a different physician at the clinic. It will be interesting to see what the Florida medical board and local law enforcement authorities make of these claims. The victim's sister, however, is clear about who is to blame, saying about Grekos, "This guy needs to be stopped."

March update - allergy testing

Sorry I haven't written .... well not really ... I haven't written because I'm just feeling good and there's nothing to add.

Oh, I got allergy testing done. Remember how I ate at Bonefish Grill and had a crusted trout, so thought that since it was Bang Bang shrimp night that I got sick from shrimp contamination? Uh, surprise surprise. It wasn't the shrimp ...... it was the pecan crust on the trout! I'm allergic to pecans, peanuts (I knew), and sunflower seeds, but not shellfish.

I got a blood test done to confirm and don't have those results yet.

Still taking:

1 drop Lugol's iodine
Blood Builder, 1 tablet
magnesium
5HTP at bedtime
Armour Thyroid
Vitamin D3

Sometimes take:

Vitamin C
other antioxidants (resveratrol, or something else)

Update: My blood test came back as mildly allergic to clams, oysters, squid, and scallops.

Slate retracts, Nature reports, McGee resigns

I was disturbed to learn yesterday that Slate has made an editorial retraction of the article "The Celltex Affair" by Carl Elliott, and issued an apology to Glenn McGee, a bioethicist who has been criticized by me and many others for his professional involvement with the troubled Texas stem cell company and RNL Bio licensee, CellTex, at a time when he was also editor-in-chief of the American Journal of Bioethics. The retraction was apparently prompted by allegations of factual error and defamation made initially by David Eller (Celltex CEO), to which Carl Elliot responded, and later by a law firm representing McGee. The excellent blog Retraction Watch has provided a nice summary of the recent developments, and Leigh Turner has posted a thoroughgoing chronicle of the events and issues that surround this case up to the day before Slate's sudden retraction. (Turner's article was published on Feb. 28, while the retraction is dated Feb. 29).


With the intensive scrutiny and crying foul over the past month, I don't know if I have a lot to add to the commentary. I do note that my blog is mentioned in the letters from Eller and DeShazo and Nesbitt, McGee's lawyers, with particular reference to a correction I made to one point in my original post on the ICMS Potemkin investigation of RNL Bio, which had stated the McGee had participated in and authored the report of an investigation of RNL's provision of cells for use in unproven treatments overseas. He emailed me stating that he was not the author of this particular report, but that he wrote a different report specifically on the company's ethical practices. I noted this both in the original post and in the more recent one on his joining CellTex, and apologized for the mistake. 


It is clearly vital to get all the facts straight, and I am happy to correct any factual errors discovered in my writing, but equally clearly many of the other disturbing facts of the case remain uncontested, and I have to wonder why Slate would decide to retract such an important story, particularly given Elliot's rebuttal, which I found to be reasonable and compelling. Perhaps Eller's decade-long libel suit against Forbes and journalist William Barrett was more compelling evidence still of the potential cost of engaging millionaires in the courts.


I should further comment on one point in Eller's accusation, which claims "Fact: Dr. McGee has no knowledge as to whether Dr. Ra served on boards" (referring to the participation of RNL Bio CEO Ra Jeong Chan on the Laboratory Advisory Board of the International Cellular Medicine Society in fall of the year when the patient deaths in Japan and China occurred. In fact, I did email Dr McGee on September 10, 2010 at his bioethics.org address prior to writing my first blog post, as I thought at the time that he might be unaware of some important aspects of the ICMS organization. 


McGee did not acknowledge or respond to this email, so I cannot say whether he actually read it, but even if he failed to familiarize himself as a director with the members of other boards, he had clear opportunity to do so just by opening his inbox. I therefore do not think this particular defense is valid, and more generally feel Elliot is owed an apology from the editor of Slate for making a retraction when a correction or clarification on several minor points would have sufficed. This is particularly true as the basis for defamation seems to rely largely on intent, and neither Eller nor the McGee lawyers seem to have done anything to show any alleged error was made intentionally on Elliott's part. 


Things get even more interesting now that Nature journalist David Cyranoski has published a nifty bit of investigative journalism on March 1, with an accompanying editorial, that lays out how CellTex delivers processed adipose cells to a local physician and pays him a commission to inject them into patients with diseases like multiple sclerosis. What's worse, the Texas Medical Board, a group of 17 political appointees less than half of whom have an MD, has drafted new regulations that appear to suggest that Texas views FDA oversight over the clinical use of investigational agents (such as stem cells) as optional. The feds may tend to disagree, as they showed last year in arresting Fredda Branyon, Vincent Dammai, Alberto Ramon, and Frank Morales for similar practices (although it was allogeneic cord blood in that case, rather than processed autologous adipose cells). 


McGee, who did not agree to be interviewed for the March 1 Nature article, abruptly announced his resignation, effective Feb. 28, from CellTex, just three months after joining the company. He also previously stepped down as editor in chief of the American Journal of Bioethics, and says via twitter he is preparing "lengthy, pointed comments on the whole matter." 


Given all the many villains and clowns in this big-money drama, we can only hope that McGee opts to redeem himself through full disclosure.

Raw Food: Ignored advice to go slow!!!

Prior to becoming ill, I ate a TON of raw food! I tried to shoot for 50% or more. I juiced often. Then, when I got sick, I couldn't digest raw food at all. :( I could only eat vegetables if they were overcooked, so soups became a favorite because who likes overcooked side dishes?

Recently, I FINALLY can eat as much raw food as I want, so as I usually do, I went overboard. I read Norman Walker's book on Weight Control .... I didn't buy it, it came with my Norwalk Juicer .... but it has good information in it about eating raw. He warns, GO SLOW, don't change over all at once. Did I listen? Of course not!!! I'm too healthy for it to have been more than a little issue!

WRONG!!!

A day in, as usual, I had a little headache. Nothing big. Hardly noticeable. Three days in, my hips started hurting so badly that the pain woke me up in the middle of the night. The pain in the morning was severe. I did okay, but not great that day. That night, the pain reminded me of when I broke my leg!! OUCH! Two and a half hours after I went to bed and couldn't sleep because I was crying over the pain, I finally got up and ate an Udi's gluten-free bagel with butter and raw almond butter on it. I took a Vicodin, and went back to bed. I played on my iPhone until the Vicodin kicked in then went to sleep.

The next morning, they hurt again, but not so bad. After my evening juice, YOWEE!!! I wasn't messing around with it a second night, so took two Advil and a Norco. I ate some organic blue corn chips and had some wild rice with my dinner salad.

Today I got up and ate my new normal raw breakfast (a glass of fresh apple juice and a couple celery stalks with raw almond butter). I had leftover salad with wild rice for lunch. Multiple raw snacks. I feel much better today, no pain.

I was worried about not having enough food, not about an intense healing reaction. I've been eating raw seed bars, raw soaked almonds, avocados, and nut butters to be sure I'm getting enough fat and calories with all the pilates I've been doing. But I hadn't taken into account that going to fast might cause a healing reaction. Wow. I learned my lesson.

Here's a good site that talks about going raw and what can happen if you go too fast -link

I don't plan on eating all raw all the time, but I am happy to get back to eating a significant amount of raw fruits and veggies full of enzymes. Interestingly, last time I started juicing, a friend who only sees me once a week was so surprised how much younger I looked after only a week of it that she went out and bought a juicer that day. This time, hubby was out of town for four days, and when he got home he said the same thing. Why do I ever stop juicing?!?! LOL

"You're eating a raw food dinner? You better not, it will make you feel like $#!T!!! Yup, my body is weird. There is really no way to know why the detox reaction is in the hips. It started soon after starting raw food, and ended soon after adding cooked back in, so it was clearly related.

Being able to eat this way again tells me that I'm significantly healed. I've been finished with treatment of infection for a couple years now, but as you know I've been working on total healing since then. I want to change my body so that it's not the same as the body that got so gravely ill. I think I'm close to the last layer .... though you never know how many there are .... but this step is significant.

My plans are to eat raw all the way until dinner .... except for today, of course.

Iodine

I've been reading a lot about iodine supplementation lately and it's fascinating. Apparently, most of the population is iodine deficient. There is less iodine in salt and over 50% of people don't use iodized salt. Junk food that is loaded with salt, is loaded with plain salt, not iodized. People in trying to be healthy, cut out salt, which, by the way, is a macronutrient and important to our health.

Recent studies show that perhaps a much higher than RDA amount of iodine is needed. This is big in cancer prevention, specifically breast and prostate cancers.

It's also big in fighting everything from fungus, candida, bacteria, parasites, heavy metals, etc. It's needed for health.

So, I did the test, that has debatable accuracy, but I did it anyway. I painted a patch of my skin with iodine. It dissappeared in less than an hour. I bought Lugol's, the iodine used for many years by doctors.

Do you know anything about bromine? Yes, the stuff used in hot tubs instead of chlorine, that's what I'm talking about. Well, do you know you eat A LOT of bromine? Bread makers used to use iodine in bread. At some point they decided to switch to bromine. it's also in brominated vegetable oil. You say you don't eat brominated vegetable oil? Well, it's in Mountain Dew, Gatorade, Fresca, and other soft drinks. Yuck.

What's the big deal about bromine? It's in the same family of elements as iodine. Your body will use it as iodine, but it can't do all the things for you that iodine does, it just takes up iodine's place in your body. Could this be why we have an epidemic of low thyroid (and even obesity?)? Could this be my answer in getting off thryoid meds once and for all?

I started supplementing a few weeks ago. In the beginning, I did salt loading (I'll provide links so you can read more about the details of this). The salt provides chloride for the kidneys so the bromide doesn't get stuck there. You guessed it. Chloride is also in the iodine family of elements. So is flouride. How can flouridation and chlorination of our water be a good idea?

Many people have bromide detoxification reactions. My husband did. He felt like he had a bad cold and fatigue for the first couple weeks. I had a worse reaction, with over half of the symptoms they say you can have. My hips ached soooo bad. I also had the "cold" and fatigue. Now my left kidney is aching, so I started back with the salt. I'm taking a couple days off the iodine to give my kidneys a rest. I've also bought supplements that are supposed to give kidney support.

Here are some links -

Bromide and salt loading

Bromide dominance

Iodine deficiency

Update and shameless advertising

Well, since I'm doing so well, I really have no HEALTH updates for you at this point. YAY!!! Nice to have nothing to say about my health, right? :)

But, I finished my first 100 hours of pilates training with my new certification program (I'm already "certified", just adding to it). It was 25 hours per week, as I told you in my last post. I took the test, both written and teaching a client, and passed!! Onto the next stage!! The next stage starts this weekend with 18 hours of training over 3 days .... over half that will be doing pilates, so I'll be exhausted by Monday when I have a 90 minute massage scheduled!

I also wanted to tell you that my daughter started blogging. It's a more fun read than this one because it's all about fun topics and has pictures. Please check it out and let me know what you think! Her Halloween post has pictures of me with the goofy husband and goofy kids.

http://luvvleighb.wordpress.com/

Update- new bloodwork

I hadn't been to a gyno since my previous one ridiculed me right out of his office. That *could* be the subject of this post, but if you have Lyme, you can imagine the story and you'd be right ... and it included saying anyone who specializes in Lyme is probably a scam ... and he was speechless when I said I had all the symptoms, a positive test, and was doing better with treatment.

Anyway, this time I went to a female gyno for the first time. It wasn't weird, LOL. She specializes in women my age (not having babies). She did a lot of blood tests and I was impressed. She actually tested for vitamin D! I asked her for a ferritin test since mine was only 24 last spring, and she did one for me. Five vials of blood.

Seems I'm NORMAL!!! Not a big accomplishment for most people, but you know what I've been through.

My ferritin is up to 66. She mentioned it was still on the low side, but that low was pretty normal for someone with periods like mine. No wonder I have more energy!!! That's a BIG jump!!! I am still taking double Blood Builder. I muscle test every day, and around my period I can test for two or three twice per day, but normal days, two only once per day.

My vitamin D is up to 64 from 35 last spring. She mentioned that I must supplement because no one is ever in range. I told her I did. She asked how much .... it's 4000-8000 IU daily.

Since I'm taking so much vitamin D and so much iron, both of which "they" say you can take too much of, I was glad to get the confirmation that my body is doing well on it. And I like this new doc. The only thing I don't like is the AIR FRESHENER!!! I could hardly breath in the waiting room. I found it odd a doctor who knows this much about health would have such toxic poison in the waiting room. I would think maybe essential oils .... but not this toxic stuff. I was wheezing at night when I lied down to go to sleep. I couldn't figure out why because that is not normal for me .... then I remembered ... had to be the air freshener. I haven't had that problem since.

I'm feeling great! I'm in a pilates training program that is 25 hours per week. I'm having to memorize tons of stuff and doing fine with it. My brain has come a long way. I'm also on average doing about two hours of pilates a day five days a week, and that's going well, too.

I am photoning monthly again for about the last four months or so. I like to use blood this time of year because so many bugs are going around. I had taken a few months off and did fine.

So, there's your update. Right now I'm taking very little:

Vitamin D
Vitamin C
Iron
Armour Thyroid (one grain)
5HTP at night
Turmeric (with all this pilates, LOL)

TWO YEARS!!!

August marked two years of being free of Lyme and coinfections!!!!

As I look back, I see how many health issues I had and how many I overcame. When I was bedridden a few years back, on an all liquid diet and in a lot of pain, I never dreamt I would be living normally in the future. I never dreamt I'd be off all medications except thyroid. I never dreamt I'd feel this good. I thought I would be on a maintenance program for the rest of my life.

Even though the Lyme and coinfections were gone two years ago, my body had a lot of other healing to do. I still had the mold toxicity because I wasn't strong enough to take the medications my doctor had prescribed. I still had muscular imbalances. My skeleton was twisted. I was toxic from the infections, mold, and treatment. My digestion was still bad.

For two years I have had chiropractic work and massages along with working out on the pilates reformer. This has rebalanced my musculature. Pilates was such a huge help for me, I got certified to teach it and now share my passion for it with others. I've been teaching for over a year and a half and am getting ready to start another rigorous certification program that will take 9 months.

I believe Pilates also helped me to reach toxins and infection that were stored deeply in muscle.

I've done many detoxification programs, and recently one for mold.

I have done things to heal my gut.

I realize that my blog sounds crazy at times with the muscle testing and working by intuition, but if you knew me when I was sick, knew me two years ago when I was infection-free, and knew me today, you'd know that though it might sound crazy, what I did worked.

Two health issues that still bother me are 1) that I still rely on thyroid supplementation, and 2) that I am deathly allergic to shellfish.

So recently I started eating grain-free. I am interested in the various so-called caveman diets, but going into teacher training again, I can't start such a strict diet at this point. I'll see how things go and maybe fully go into one of them after the first of the year. These diets are supposed to heal the gut, which helps allergies. I've also read how it can help with hormones and even iron, which I still have to supplement. I'm willing to give it a try. Maybe by this time next year my gut will be even healthier and my allergies will be lessened. The shellfish allergy will likely always be here, but maybe I can eat in a restaurant without worrying that one of the cooks *touched* a shrimp that day. I believe I should be able to get rid of food intolerances, like to peaches.

The grain-free diet has been interesting. I'm glad I didn't start out with the strict introductory phase. It's lower carb than I'm used to, so it's a challenge. I'll keep you posted on how it goes. At some point I'll have to get back into the fermented foods, but right now I'm taking it one step at a time.

I think I'll always sound a little bit crazy, but at this point, I'm working to keep getting healthier ..... I've already reached good health. And I'll always be doing some kind of detox program .... right now, I'm on my yearly Dr. Natura but added Toxinout this time. So far, so good.

ADHD and Vitamin D Deficiency: Any Evidence?

Is there any link between vitamin D levels and ADHD? A review of the current evidence:

We have spent a lot of time looking at correlations between vitamins, minerals, omega-3 fatty acids and amino acids (and their deficiencies) and ADHD. However, it is important to note that just because low levels of a particular nutrient are seen alongside the disorder, it does not necessarily mean that this deficiency is the cause of ADHD (i.e. correlation does not imply causation). In other words, the nutrient deficiency and ADHD symptoms might both be secondary effects of a larger primary cause, such as an enzyme deficiency or metabolic dysfunction.

In the case of vitamin D, the association with ADHD is a lot more muddled than with some of the other nutrients which have a relatively strong connection with the disorder (iron, zinc, magnesium, and omega-3 fatty acids to name a few). The amount of information in the literature is relatively scarce, as well. A search in the journal database Pubmed (where this blogger gets most of his articles and information) for "ADHD" and "vitamin D" turns up only a small handful of search results, the majority of which focus on other disorders and only mention ADHD peripherally.

However, given the fact that vitamin D is such a "hot" vitamin and has been a popular supplement as of late, we should investigate some of its potential benefits with regard to ADHD and related disorders. Please keep in mind that many of these points below are more theoretical or speculative, because most of the hard, concrete evidence in well-documented clinical controlled studies simply does not exist at the moment. Nevertheless, here are some possible ways in which vitamin D may help in cases of ADHD or related disorders:

• Vitamin D can boost levels of the antioxidant glutathione in the brain. One way that vitamin D does this is by regulating an enzyme called gamma-glutamyl transpeptidase, which plays a role in both the metabolism and recycling of glutathione. We have spoken at length about how antioxidant deficits can worsen ADHD symtpoms, and how fatty acids (namely omega-3's) are frequently administered for ADHD and related disorders. Given the high makeup of these omega-3 fatty acids in the brain, and their susceptibility to oxidation and damage in the central nervous system, protecting them by boosting antioxidant levels (either directly or indirectly) is a good bet.
  
  
• One of the current theories surrounding ADHD is that it is (at least partially) an energy deficiency syndrome, or is the result of impaired metabolic abilities in key regions of the central nervous system. While highly debatable, this theory holds that impaired glucose metabolism in various parts of the brain may be a major contributing factor to the presence or severity of this disorder.
  
  While this blogger is currently neutral on this deficiency theory, it is interesting to note that vitamin D can help regulate glucose tranport into the brain, which would (at least in theory) improve this possible cause of the disorder. It is believed that vitamin D works by targeting multiple enzymes involved in glucose transport and metabolism. Much more study needs to be done to confirm this assertion, but this may be another potential benefit of boosting vitamin D levels in the ADHD patient.
  
  
• Vitamin D may play a role in catecholamine synthesis. Catecholamines include the neurotransmitters dopamine and norepinephrine, both of which are believed to be tightly regulated and highly involved in the treatment of ADHD (deficiencies of both dopamine and norepinephrine in the "gaps" between neuronal cells are often seen in cases of ADHD).
  
  
• Vitamin D boosts the effects of an enzyme called choline acetyltransferase in the mammalian brain. This enzyme is used in the manufacture of another neurotransmitting agent called acetylcholine. Acetylcholine is thought to play a major role in maintaining a state of sustained attention, a critical shortcoming in those with ADHD. In other words, keeping adequate levels of vitamin D could potentially help prop up lower levels of this attention-sustaining neurochemical.
  
  
• Learning and memory deficits, both of which are heavily present in the ADHD population, have been tied to prenatal vitamin D deficiencies in the rat model. This involves a process called synaptic plasticity, which relates to memory formation in an individual. If this finding extends to humans, it could have serious implications on maintaining adequate vitamin D intake in pregnant women.
  
  
• Problems with fine motor control are sometimes seen as a secondary characteristic in a fraction of the ADHD population. These problems may be exacerbated in a vitamin D deficient state.
  
  
• Perhaps the strongest correlation, however, may be between vitamin D and depressive-like symptoms, particularly those associated with seasonal affective disorders (SAD). Please keep in mind, however, that studies on vitamin D levels and depression are highly variable; a number of studies have been done on the topic and found no such linkage between the two. We have previously investigated possible connections between ADHD and SAD in an earlier post.
  
  This may make intuitive sense, since vitamin D production is triggered by sunlight, so in the dark winter months, the levels of this vitamin are often much lower (this may also be a major contributing factor as to why illnesses run so much more rampant during the winter months). In other words, vitamin D supplementation may be particularly useful in individuals with ADHD who also have co-occuring depressive or anxiety-ridden symptoms.

To summarize: Vitamin D does not have as many pronounced direct effects on ADHD as do some of the other vitamins, minerals, fatty acids and amino acids we have previously discussed. Nevertheless, the vitamin does seem to have multiple neurodevelopmental and neuroregulatory properties, and may go well with comorbid disorders such as schizophrenia, speech difficulties, memory problems, and (perhaps most strongly) depressive symptoms. Please keep in mind, however, that it may not be possible to simply "supplement these problems away" with extra vitamin D. This blogger just wants to point out that a deficiency in this vitamin often manifests itself in many ways, some of which closely parallel ADHD or related disorders. Nevertheless, supplementing may not be a bad idea, especially if you live in an area that gets minimal sunlight for part of (or all of) the year. Some rough guidelines for vitamin D intake can be found here.